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Standards Ontologies Notations
cytochrome P450 family 2 subfamily J member 2

Summary
Gene Symbol
  • CYP2J2
Organism
Homo sapiens (human)
External Links
NCBI Gene
1573
HGNC
2634
KEGG Gene ID
hsa:1573
PubChem
1573
Alliance of Genome Resources
Annotation
Keyword
  • Direct protein sequencing
  • Fatty acid metabolism
  • Heme
  • Isomerase
  • Membrane
  • Microsome
  • Monooxygenase
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
P51589
  • Albendazole monooxygenase (hydroxylating)
  • Albendazole monooxygenase (sulfoxide-forming)
  • Arachidonic acid epoxygenase
  • CYPIIJ2
  • Hydroperoxy icosatetraenoate isomerase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
regulation of heart contraction
epoxygenase P450 pathway
fatty acid metabolic process
icosanoid metabolic process
organic acid metabolic process
GO Hierarchy
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
hydroperoxy icosatetraenoate isomerase activity
linoleic acid epoxygenase activity
monooxygenase activity
iron ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K07418
Name
cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
References
Rhea

RHEA:55560

a hydroperoxyeicosatetraenoate
a hydroxy-epoxy-eicosatetraenoate
Enzyme
PMID

RHEA:55928

O2 + fenbendazole
H2O + H+ + fenbendazole S-oxide
Enzyme
PMID

RHEA:37931

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
(10R)-hydroxy-(8S,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:37939

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(8R)-hydroxy-(11R,12R)-epoxy-(5Z,9E,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:37951

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(10R)-hydroxy-(11S,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:55924

O2 + albendazole
H2O + H+ + albendazole S-oxide
Enzyme
PMID

RHEA:37955

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(8R)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:37959

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
(13R)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate
Enzyme
PMID

RHEA:56288

O2 + albendazole
hydroxyalbendazole + H2O + H+
Enzyme
PMID
Disease
Disease Ontology
Displaying entries 11 - 20 of 83 in total
DO ID Disease Name Source
DOID:0080348 Alzheimer's disease 1
DOID:0110035 Alzheimer's disease 2
DOID:0110037 Alzheimer's disease 5
DOID:0110038 Alzheimer's disease 6
DOID:0110039 Alzheimer's disease 7
DOID:0110041 Alzheimer's disease 8
DOID:0110043 Alzheimer's disease 10
DOID:0110044 Alzheimer's disease 11
DOID:0110045 Alzheimer's disease 12
DOID:0110046 Alzheimer's disease 13
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002292
Gene Name
cytochrome P450, family 2, subfamily J, polypeptide 2
Ortholog
Displaying entries 1 - 10 of 123 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
178803 WB:WBGene00019472
179148 WB:WBGene00015709
181850 WB:WBGene00015043
181851 WB:WBGene00015044
181852 WB:WBGene00015045
182176 WB:WBGene00015399
182177 WB:WBGene00015400
182888 WB:WBGene00016092
183622 WB:WBGene00016786
187209 WB:WBGene00019565
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024