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Standards Ontologies Notations
cytochrome P450 family 2 subfamily J member 2

Summary
Gene Symbol
  • CYP2J2
Organism
Homo sapiens (human)
NCBI Gene
1573
HGNC
2634
KEGG Gene ID
hsa:1573
PubChem
1573
Alliance of Genome Resources
Annotation
Keyword
  • Direct protein sequencing
  • Fatty acid metabolism
  • Heme
  • Isomerase
  • Membrane
  • Microsome
  • Monooxygenase
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
P51589
  • Albendazole monooxygenase (hydroxylating)
  • Albendazole monooxygenase (sulfoxide-forming)
  • Arachidonic acid epoxygenase
  • CYPIIJ2
  • Hydroperoxy icosatetraenoate isomerase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
icosanoid metabolic process
regulation of heart contraction
linoleic acid metabolic process
epoxygenase P450 pathway
xenobiotic metabolic process
GO Hierarchy
Displaying entries 1 - 5 of 11 in total
GO Term Evidence Code PMID
arachidonic acid epoxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
arachidonic acid 14,15-epoxygenase activity
arachidonic acid 11,12-epoxygenase activity
linoleic acid epoxygenase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Cytochrome P450
Functional Category
  • C: Energy production and conversion
  • I: Lipid transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
Displaying all 4 entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450
KEGG BRITE Database
Orthology
K07418
Name
cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
References
Rhea

RHEA:55560

a hydroperoxyeicosatetraenoate
a hydroxy-epoxy-eicosatetraenoate
Enzyme
PMID

RHEA:37939

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(8R)-hydroxy-(11R,12R)-epoxy-(5Z,9E,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:37931

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
(10R)-hydroxy-(8S,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:37959

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
(13R)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate
Enzyme
PMID

RHEA:55928

O2 + fenbendazole
H2O + H+ + fenbendazole S-oxide
Enzyme
PMID

RHEA:37955

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(8R)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:56288

O2 + albendazole
hydroxyalbendazole + H2O + H+
Enzyme
PMID

RHEA:37951

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
(10R)-hydroxy-(11S,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate
Enzyme
PMID

RHEA:55924

O2 + albendazole
H2O + H+ + albendazole S-oxide
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002292
Gene Name
cytochrome P450, family 2, subfamily J, polypeptide 2
Ortholog
Displaying entries 11 - 20 of 124 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
181850 WB:WBGene00015043
181851 WB:WBGene00015044
181852 WB:WBGene00015045
182176 WB:WBGene00015399
182177 WB:WBGene00015400
182888 WB:WBGene00016092
183622 WB:WBGene00016786
187209 WB:WBGene00019565
188400 WB:WBGene00011699
189364 WB:WBGene00021168
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024