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interleukin 18 receptor 1

Summary

Gene Symbol

Il18r1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16182

PubChem

16182

Alliance of Genome Resources

MGI:105383

Annotation

Keyword

Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
Inflammatory response
NAD
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8C257
Q61098	CD218 antigen-like family member A IL1 receptor-related protein Interleukin-18 receptor alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
adaptive immune response	IBA
inflammatory response	IEA
natural killer cell activation	IMP	10227969
type II interferon production	IMP	10227969
positive regulation of type II interferon production	ISS

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

immune response [inference]

adaptive immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

natural killer cell activation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

natural killer cell activation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

interleukin-18-mediated signaling pathway

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

type II interferon production

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

natural killer cell activation

T cell activation [inference]

T cell activation involved in immune response [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell activation [inference]

alpha-beta T cell activation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell activation [inference]

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

cytokine production [inference]

type II interferon production

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation [inference]

T cell differentiation involved in immune response [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

alpha-beta T cell differentiation [inference]

alpha-beta T cell differentiation involved in immune response [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

CD4-positive, alpha-beta T cell differentiation [inference]

CD4-positive, alpha-beta T cell differentiation involved in immune response [inference]

T-helper cell differentiation [inference]

T-helper 1 cell differentiation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

negative regulation of metabolic process [inference]

negative regulation of cold-induced thermogenesis

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cold-induced thermogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

interleukin-18-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

negative regulation of multicellular organismal process [inference]

negative regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

negative regulation of cold-induced thermogenesis

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
cell surface	IBA
membrane
interleukin-18 receptor complex	ISO
interleukin-18 receptor complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-18 receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-18 receptor complex

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

Displaying entries **1 - 5** of 9 in total

1

2

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Last »
GO Term	Evidence Code	PMID
NAD+ nucleosidase activity
protein binding	IPI	26099046
interleukin-18 binding	ISS
interleukin-18 binding	ISO
interleukin-18 receptor activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

protein binding

cytokine binding [inference]

interleukin-18 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

interleukin-18 receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-18 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

interleukin-1 receptor accessory protein-like

Functional Category

L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
interleukin-18 binding
interleukin-18 receptor activity

Displaying **all 4** entries
InterPro
Immunoglobulin-like fold
Interleukin-1 receptor family
Toll/interleukin-1 receptor homology (TIR) domain superfamily
Toll/interleukin-1 receptor homology (TIR) domain

Rhea

RHEA:16301

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8809	HGNC:5988	HUMAN64134
Homo sapiens	16182	HGNC:5988
Rattus norvegicus	301365		RATNO44061
Bos taurus	407221		BOVIN02058
Felis catus	493938		FELCA08015
Canis lupus familiaris	611438		CANLF01741
Monodelphis domestica	100017899		MONDO31436
Oryctolagus cuniculus	100303768		RABIT08288
Callithrix jacchus	100394659		CALJA11239
Macaca mulatta	100426588		MACMU08681

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

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Acknowledgements