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interleukin 9 receptor

Summary

Gene Symbol

Il9r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16199

PubChem

16199

Alliance of Genome Resources

MGI:96564

Annotation

Keyword

3D-structure
Cell membrane
Glycoprotein
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q01114
A2AVE0
Q78PA5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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2

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GO Term	Evidence Code	PMID
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	IGI IMP	18551134
regulation of peptidyl-tyrosine phosphorylation	IGI	30082831
B cell proliferation	IGI	30082831
cytokine-mediated signaling pathway	IBA
positive regulation of cell growth	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-9-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

B cell mediated immunity [inference]

immunoglobulin mediated immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth

positive regulation of cellular process [inference]

positive regulation of cell growth

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interleukin-9-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell growth

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity [inference]

regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

negative regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [inference]

negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
plasma membrane	IDA ISO	30082831
extracellular region	IEA
cell surface	IDA	30082831

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
interleukin-9 binding	IBA ISO
interleukin-9 receptor activity	IBA IGI ISO	30082831

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding [inference]

interleukin-9 binding

cytokine binding [inference]

interleukin-9 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

interleukin-9 receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-9 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

interleukin-9 receptor

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
cytokine-mediated signaling pathway
interleukin-9 binding
interleukin-9 receptor activity

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1485	cystic fibrosis	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3581		HGNC:6030	HUMAN103012
Rattus norvegicus	24500	10116_1:003818	RGD:2907	RATNO02083
Canis lupus familiaris	611642			CANLF16785
Macaca mulatta	704266			MACMU47598
Equus caballus	100066258			HORSE07193
Callithrix jacchus	100408034			CALJA48535
Sus scrofa	100521616			PIGXX21306
Nomascus leucogenys	100582570			NOMLE38955
Loxodonta africana	100654245			LOXAF06843
Cavia porcellus	100716584	10141_0:004663

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements