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decorin
Summary
- Gene Symbol
-
- DCN
- Aliases
-
- DSPG2
- SLRR1B
- decorin proteoglycan
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of angiogenesis | ||
| negative regulation of endothelial cell migration | ||
| positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | ||
| positive regulation of macroautophagy | ||
| positive regulation of mitochondrial depolarization |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| Golgi lumen |
|
|
| collagen-containing extracellular matrix | ||
| extracellular space | ||
| lysosomal lumen |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix structural constituent conferring compression resistance | ||
| extracellular matrix binding | ||
| protein binding | ||
| glycosaminoglycan binding | ||
| RNA binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060584 | Noonan syndrome 6 | |
| DOID:0060585 | Noonan syndrome 7 | |
| DOID:0060586 | Noonan syndrome 8 | |
| DOID:0060587 | Noonan syndrome 9 | |
| DOID:0060588 | Noonan syndrome 10 | |
| DOID:0060608 | microcephalic osteodysplastic primordial dwarfism type I | |
| DOID:0060609 | microcephalic osteodysplastic primordial dwarfism type II | |
| DOID:0060642 | recessive dystrophic epidermolysis bullosa | |
| DOID:0060644 | chondrodysplasia-pseudohermaphroditism syndrome | |
| DOID:0060762 | restrictive dermopathy |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000486 | Strabismus |
| HP:0000501 | Glaucoma |
| HP:0000529 | Progressive visual loss |
| HP:0000613 | Photophobia |
| HP:0001131 | Corneal dystrophy |
| HP:0003623 | Neonatal onset |
| HP:0007709 | Band-shaped corneal dystrophy |
| HP:0011487 | Increased corneal thickness |
| HP:0200020 | Corneal erosion |
| Disease ID | Disease Name |
|---|---|
| OMIM:610048 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100079988 | ORNAN05913 | ||
| 103114556 | ERIEU08332 | ||
| 100405391 | CALJA44915 | ||
| 105572760 | CERAT43317 | ||
| 101866144 | MACFA04019 | ||
| 709933 | MACMU03728 | ||
| 105483740 | MACNE23852 | ||
| 101018003 | PAPAN40942 | ||
| 105545870 | MANLE16867 | ||
| 101133609 | GORGO05791 |
