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interferon lambda receptor 1

Summary

Gene Symbol

IFNLR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

163702

PubChem

163702

Alliance of Genome Resources

HGNC:18584

Annotation

Keyword

3D-structure
Alternative splicing
Antiviral defense
Disulfide bond
Glycoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IU57	Cytokine receptor class-II member 12 Cytokine receptor family 2 member 12 Interleukin-28 receptor subunit alpha Likely interleukin or cytokine receptor 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
positive regulation of cellular respiration	IMP	25930096
response to type III interferon	ISS
cellular response to virus	NAS	30936491
mucosal immune response	ISS
negative regulation of cell population proliferation	NAS	12469119

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type III interferon-mediated signaling pathway

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type III interferon

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

positive regulation of cellular respiration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host

regulation of response to external stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type III interferon-mediated signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

positive regulation of cellular respiration

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular respiration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA TAS
membrane	NAS	12483210
interleukin-28 receptor complex	IDA	12469119

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-28 receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

interleukin-28 receptor complex

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12469119 12483210 32296183
cytokine receptor activity	IBA NAS	12483210

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	3455	ZFIN:ZDB-GENE-070905-2
Danio rerio	3587	ZFIN:ZDB-GENE-071120-5
Danio rerio	16154	ZFIN:ZDB-GENE-071120-5
Xenopus tropicalis	163702	Xenbase:XB-GENE-6462098
Mus musculus	242700	Xenbase:XB-GENE-6462098	MOUSE40934
Rattus norvegicus	362628		RATNO32681
Pan troglodytes	456628		PANTR20256
Bos taurus	616826		BOVIN25186
Macaca mulatta	711625		MACMU22011
Monodelphis domestica	100011283		MONDO25122