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MIRAGE
dynactin subunit 1
Summary
- Gene Symbol
-
- DCTN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amyotrophic lateral sclerosis
- Coiled coil
- Cytoskeleton
- Dynein
- Microtubule
- Mitosis
- Neuropathy
- Nucleus
- Parkinsonism
- Phosphoprotein
- Reference proteome
- Transport
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| melanosome transport | ||
| microtubule anchoring at centrosome | ||
| retrograde transport, endosome to Golgi | ||
| neuromuscular process | ||
| nuclear membrane disassembly |
GO Hierarchy
biological process
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinetochore | ||
| kinetochore | ||
| spindle pole | ||
| spindle pole | ||
| nuclear envelope |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| tau protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Dynactin subunit 1
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytoplasmic microtubule organization |
| microtubule plus-end binding |
| InterPro |
|---|
| CAP Gly-rich domain superfamily |
| CAP Gly-rich domain |
| Dynein associated protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060193 | amyotrophic lateral sclerosis type 1 | |
| DOID:0060486 | Perry syndrome | |
| DOID:0111202 | autosomal dominant distal hereditary motor neuronopathy 14 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100174308 | PONAB23439 | ||
| 100230170 | TAEGU23692 | ||
| 100346609 | RABIT08513 | ||
| 100401682 | CALJA10966 | ||
| 100475411 | AILME10492 | ||
| 100519249 | PIGXX21774 | ||
| 100558573 | ANOCA12524 | ||
| 100585622 | NOMLE08371 | ||
| 100656316 | LOXAF10990 | ||
| 100714202 | CAVPO15004 |
