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MIRAGE
inositol 1,4,5-triphosphate receptor 3
Summary
- Gene Symbol
-
- Itpr3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Calcium channel
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Ligand-gated ion channel
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P70227 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion transport | ||
| G protein-coupled receptor signaling pathway | ||
| positive regulation of cytosolic calcium ion concentration | ||
| memory | ||
| calcium-mediated signaling |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nuclear envelope | ||
| nuclear outer membrane | ||
| nucleoplasm | ||
| nucleolus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| inositol hexakisphosphate binding | ||
| inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | ||
| inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | ||
| inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- inositol 1,4,5-trisphosphate receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| RIH domain |
| Ryanodine/Inositol 1,4,5-trisphosphate receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3708 | FB:FBgn0010051 | ||
| 3709 | FB:FBgn0010051 | ||
| 3710 | Xenbase:XB-GENE-1012312 | HUMAN84359 | |
| 16438 | FB:FBgn0010051 | ||
| 16440 | Xenbase:XB-GENE-1012312 | ||
| 25262 | FB:FBgn0010051 | ||
| 25679 | RATNO22044 | ||
| 281879 | BOVIN18302 | ||
| 462618 | PANTR37920 | ||
| 481746 | CANLF02641 |
