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jagged 1

Summary

Gene Symbol

Jag1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16449

PubChem

16449

Alliance of Genome Resources

MGI:1095416

Annotation

Keyword

Calcium
Cell membrane
Developmental protein
Disulfide bond
EGF-like domain
Glycoprotein
Notch signaling pathway
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UVN4
Q9QXX0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 41 in total

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GO Term	Evidence Code	PMID
ciliary body morphogenesis	IMP	23676271
neuron differentiation	IMP	20081190
pulmonary artery morphogenesis	ISO ISS
cardiac right ventricle morphogenesis	IMP	19509466
podocyte development	IMP	23806616

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

neuroendocrine cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

neuroepithelial cell differentiation [inference]

neuroendocrine cell differentiation

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development

stem cell development [inference]

neural crest cell development [inference]

cardiac neural crest cell development involved in heart development [inference]

cardiac neural crest cell development involved in outflow tract morphogenesis

cardiac cell development [inference]

endocardial cushion cell development

multicellular organismal process [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

tissue remodeling [inference]

blood vessel remodeling

developmental process [inference]

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

pulmonary valve morphogenesis

cardiac chamber morphogenesis [inference]

cardiac ventricle morphogenesis [inference]

cardiac right ventricle morphogenesis

animal organ morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis [inference]

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of an epithelial sheet

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

renal tubule development [inference]

nephron tubule development [inference]

kidney epithelium development [inference]

nephron epithelium development [inference]

nephron tubule development [inference]

tube development [inference]

renal tubule development [inference]

nephron tubule development [inference]

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development

stem cell development [inference]

neural crest cell development [inference]

cardiac neural crest cell development involved in heart development [inference]

cardiac neural crest cell development involved in outflow tract morphogenesis

cardiac cell development [inference]

endocardial cushion cell development

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

camera-type eye development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

mechanoreceptor differentiation [inference]

inner ear receptor cell differentiation [inference]

inner ear auditory receptor cell differentiation

neuroendocrine cell differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

neuroepithelial cell differentiation [inference]

neuroendocrine cell differentiation

epidermal cell differentiation [inference]

hair cell differentiation [inference]

inner ear auditory receptor cell differentiation

cell development [inference]

epithelial cell development [inference]

glomerular epithelial cell development [inference]

podocyte development

stem cell development [inference]

neural crest cell development [inference]

cardiac neural crest cell development involved in heart development [inference]

cardiac neural crest cell development involved in outflow tract morphogenesis

cardiac cell development [inference]

endocardial cushion cell development

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to muramyl dipeptide

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to muramyl dipeptide

response to oxygen-containing compound [inference]

response to peptide [inference]

response to muramyl dipeptide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

positive regulation of myeloid cell differentiation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-cell adhesion

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of developmental process [inference]

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

inhibition of neuroepithelial cell differentiation

regulation of development, heterochronic [inference]

regulation of timing of cell differentiation [inference]

inhibition of neuroepithelial cell differentiation

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

negative regulation of endothelial cell differentiation

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of fat cell differentiation [inference]

negative regulation of fat cell differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of timing of cell differentiation [inference]

inhibition of neuroepithelial cell differentiation

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

positive regulation of myeloid cell differentiation

regulation of stem cell differentiation [inference]

negative regulation of stem cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

negative regulation of endothelial cell differentiation

regulation of embryonic development [inference]

inhibition of neuroepithelial cell differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

positive regulation of myeloid cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-cell adhesion

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cell population proliferation

regulation of epithelial cell proliferation

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of cardiac epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

negative regulation of endothelial cell differentiation

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of fat cell differentiation [inference]

negative regulation of fat cell differentiation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of timing of cell differentiation [inference]

inhibition of neuroepithelial cell differentiation

regulation of cell development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

positive regulation of myeloid cell differentiation

regulation of stem cell differentiation [inference]

negative regulation of stem cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-substrate adhesion [inference]

negative regulation of cell-matrix adhesion

negative regulation of cell-cell adhesion

negative regulation of cell differentiation

negative regulation of epithelial cell differentiation [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition [inference]

positive regulation of cardiac epithelial to mesenchymal transition

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

negative regulation of epithelial cell differentiation [inference]

regulation of endothelial cell differentiation [inference]

negative regulation of endothelial cell differentiation

regulation of embryonic development [inference]

inhibition of neuroepithelial cell differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

positive regulation of myeloid cell differentiation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	ISO
apical plasma membrane	IDA	24715457
plasma membrane	IDA ISO TAS	16000382 16495313
adherens junction	IDA	24715457
apical part of cell	IDA	15821257

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

apical part of cell

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GO Term	Evidence Code	PMID
protein binding	IPI	15574878 15788413 16000382
receptor ligand activity	ISO
phospholipid binding	IEA ISO
Notch binding	IBA IPI ISO	10551863 10958687
molecular adaptor activity	IEA ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

lipid binding [inference]

phospholipid binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular adaptor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein jagged-1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
Notch binding
calcium ion binding
cell communication

Displaying **all 10** entries
InterPro
Delta/Serrate/lag-2 (DSL) protein
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-like, conserved site
EGF-type aspartate/asparagine hydroxylation site
Growth factor receptor cysteine-rich domain superfamily
Jagged/Serrate protein
Notch ligand, N-terminal domain
VWFC domain

Disease

Disease Ontology

Displaying **all 10** entries
DO ID	Disease Name	Source
DOID:10595	Charcot-Marie-Tooth disease	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:13375	temporal arteritis	Alliance of Genome Resources
DOID:1682	congenital heart disease	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources
DOID:3770	pulmonary fibrosis	Alliance of Genome Resources
DOID:6419	tetralogy of Fallot	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:8398	osteoarthritis	Alliance of Genome Resources
DOID:9245	Alagille syndrome	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	182		HGNC:6188	HUMAN56107
Rattus norvegicus	29146	10116_1:0014fa	RGD:2937	RATNO26622
Drosophila melanogaster	43275		FB:FBgn0004197
Danio rerio	140421		ZFIN:ZDB-GENE-011128-2
Danio rerio	140423		ZFIN:ZDB-GENE-011128-4	DANRE05867
Canis lupus familiaris	485769			CANLF09294
Macaca mulatta	718580			MACMU01270
Pan troglodytes	748073			PANTR24369
Ovis aries	780486			SHEEP04094
Bos taurus	783681			BOVIN04219

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements