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MIRAGE
potassium voltage-gated channel, Isk-related subfamily, member 1
Summary
- Gene Symbol
-
- Kcne1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Direct protein sequencing
- Glycoprotein
- Phosphoprotein
- Potassium channel
- Reference proteome
- Transmembrane helix
- Voltage-gated channel
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of heart rate by cardiac conduction | ||
| epithelial cell maturation | ||
| positive regulation of potassium ion transmembrane transport | ||
| potassium ion export across plasma membrane | ||
| potassium ion transmembrane transport |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
negative regulation of transport [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of transmembrane transport [inference]
negative regulation of cellular process [inference]
regulation of biological quality [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| apical plasma membrane | ||
| plasma membrane | ||
| Z disc | ||
| voltage-gated potassium channel complex | ||
| membrane raft |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | ||
| transmembrane transporter binding | ||
| voltage-gated potassium channel activity | ||
| protein binding | ||
| telethonin binding |
GO Hierarchy
molecular function
transporter activity [inference]
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060224 | atrial fibrillation | |
| DOID:0110647 | long QT syndrome 5 | |
| DOID:2842 | Jervell-Lange Nielsen syndrome | |
| DOID:2843 | long QT syndrome | |
| DOID:4440 | seminoma | |
| DOID:6000 | congestive heart failure |
