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kinesin family member 3A

Summary

Gene Symbol

Kif3a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16568

PubChem

16568

Alliance of Genome Resources

MGI:107689

Annotation

Keyword

3D-structure
ATP-binding
Cilium
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Signal

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q3TET1
Q3UF02
Q3UI47
B1AQZ2
P28741	Microtubule plus end-directed kinesin motor 3A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 41 in total

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GO Term	Evidence Code	PMID
dorsal/ventral neural tube patterning	IMP	18590716 19286674 21209331
dorsal/ventral neural tube patterning	IGI	18590716
neural tube development	IMP	10330409
forebrain development	IMP	28291836
microtubule anchoring at centrosome	IMP	23386061

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule anchoring [inference]

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

microtubule-based movement [inference]

cilium movement

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

cell population proliferation [inference]

epithelial cell proliferation [inference]

keratinocyte proliferation

neural precursor cell proliferation

cell cycle process [inference]

centriole-centriole cohesion

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein localization to cell junction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule anchoring [inference]

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification

dorsal/ventral pattern formation

dorsal/ventral neural tube patterning

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

epidermal stem cell homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

embryonic morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue development [inference]

epidermis development

epithelium development [inference]

neural tube development

tube development [inference]

neural tube development

animal organ development [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

epidermal stem cell homeostasis

localization [inference]

protein-containing complex localization [inference]

receptor localization to synapse [inference]

anterograde dendritic transport of neurotransmitter receptor complex

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein localization to cell junction

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

protein localization to cell junction

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of keratinocyte proliferation

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment or maintenance of cell polarity regulating cell shape

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of keratinocyte proliferation

regulation of epithelial cell proliferation [inference]

regulation of keratinocyte proliferation [inference]

positive regulation of keratinocyte proliferation

positive regulation of epithelial cell proliferation

positive regulation of keratinocyte proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of keratinocyte proliferation

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of biological quality [inference]

regulation of cell shape [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
centrosome	ISO
centriole	ISO
centriole	IDA	23386061
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

kinesin II complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

microtubule organizing center [inference]

centrosome

cell junction [inference]

synapse [inference]

ciliary transition zone [inference]

photoreceptor connecting cilium

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

motile cilium

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

cilium

motile cilium

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

cytoskeleton [inference]

microtubule cytoskeleton

cell body [inference]

neuronal cell body

postsynapse

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

spindle microtubule

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	IBA
microtubule motor activity	IEA
protein binding	IPI	12821668 16632484 17825299 17898177 19015237 19384852 19940036 21909995 22632975 23386061 31746486
ATP binding	IEA
microtubule binding	IDA	17360631

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

GTPase binding [inference]

small GTPase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinesin

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding
spindle elongation

Displaying **all 5** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080322	polycystic kidney disease	Alliance of Genome Resources
DOID:1934	dysostosis	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements