GlyCosmos Portal

Submissions

kallikrein 1-related peptidase b1

Summary

Gene Symbol

Klk1b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16623

PubChem

16623

Alliance of Genome Resources

MGI:892019

Annotation

Keyword

Disulfide bond
Glycoprotein
Reference proteome
Serine protease
Signal
Zymogen

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A1R3UCH6
P00755	Glandular kallikrein K1 Tissue kallikrein-1
Q8C232

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
tissue kallikrein-kinin cascade	IMP
bradykinin biosynthetic process	IMP
regulation of systemic arterial blood pressure	IMP
regulation of systemic arterial blood pressure	IBA
left ventricular cardiac muscle tissue morphogenesis	IMP

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

protein metabolic process [inference]

proteolysis

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

protein activation cascade [inference]

kinin cascade [inference]

tissue kallikrein-kinin cascade

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

protein activation cascade [inference]

kinin cascade [inference]

tissue kallikrein-kinin cascade

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

protein activation cascade [inference]

kinin cascade [inference]

tissue kallikrein-kinin cascade

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

protein metabolic process [inference]

proteolysis

protein processing [inference]

zymogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation

protein activation cascade [inference]

kinin cascade [inference]

tissue kallikrein-kinin cascade

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

bradykinin biosynthetic process

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction [inference]

striated muscle contraction [inference]

cardiac muscle contraction

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

vasodilation

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

ventricular cardiac muscle tissue morphogenesis [inference]

left ventricular cardiac muscle tissue morphogenesis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

acute inflammatory response [inference]

kinin cascade [inference]

tissue kallikrein-kinin cascade

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

vasodilation

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
acrosomal vesicle	ISO
extracellular space	ISO
extracellular space	IBA
nucleus	ISO
secretory granule	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

acrosomal vesicle

apical part of cell

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
endopeptidase activity	ISO
serine-type endopeptidase activity	ISO
serine-type endopeptidase activity	IBA
serine-type endopeptidase activity	IEA
serine-type peptidase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

serine hydrolase activity [inference]

serine-type peptidase activity

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

serine-type endopeptidase activity

serine-type peptidase activity

serine-type endopeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isoform A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
proteolysis
serine-type endopeptidase activity

Displaying **all 6** entries
InterPro
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain
Serine proteases, trypsin family, histidine active site
Serine proteases, trypsin family, serine active site