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laminin, alpha 5

Summary

Gene Symbol

Lama5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16776

PubChem

16776

Alliance of Genome Resources

MGI:105382

Annotation

Keyword

3D-structure
Basement membrane
Cell adhesion
Coiled coil
Direct protein sequencing
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TZ05
Q61001	Laminin-10 subunit alpha Laminin-11 subunit alpha Laminin-15 subunit alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **21 - 25** of 26 in total

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GO Term	Evidence Code	PMID
cilium assembly	IMP	16365040
integrin-mediated signaling pathway	IEA ISO
hair follicle development	IMP	18676816
kidney development	IMP	27002738
regulation of cell migration	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

trunk neural crest cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

postsynapse organization

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

molting cycle process [inference]

hair cycle process [inference]

hair follicle development

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

animal organ morphogenesis

odontogenesis [inference]

odontogenesis of dentin-containing tooth

skeletal system morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

anatomical structure development [inference]

animal organ development [inference]

muscle structure development [inference]

muscle organ development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell adhesion

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
neuromuscular junction	IDA	9396756

GO Hierarchy

cellular component

protein-containing complex [inference]

laminin complex [inference]

cellular anatomical entity [inference]

extracellular region

synaptic cleft

extracellular space

cell junction [inference]

synapse [inference]

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
integrin binding	IDA ISO	11741585
extracellular matrix structural constituent	IBA RCA	22159717 28071719
protein binding	IPI	12743034

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:2590	familial nephrotic syndrome	Alliance of Genome Resources
DOID:2975	cystic kidney disease	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.1.1

Last updated: February 17, 2025

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