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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
latent transforming growth factor beta binding protein 3
Summary
- Gene Symbol
-
- Ltbp3
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- EGF-like domain
- Extracellular matrix
- Glycoprotein
- Growth factor binding
- Reference proteome
- Repeat
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q61810 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of mesenchymal stem cell differentiation | ||
| bone mineralization | ||
| transforming growth factor beta receptor signaling pathway | ||
| chondrocyte differentiation | ||
| negative regulation of bone mineralization |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular matrix | ||
| collagen-containing extracellular matrix | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| transforming growth factor beta binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- latent-transforming growth factor beta-binding protein 3
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| Golgi to vacuole transport |
| calcium ion binding |
| growth factor binding |
| protein targeting to vacuole |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0090143 | brachyolmia-amelogenesis imperfecta syndrome | |
| DOID:0111727 | geleophysic dysplasia 3 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4054 | HGNC:6716 | HUMAN07157 | ||
| 83838 | 10116_1:0000b5 | RGD:62057 | RATNO20483 | |
| 532772 | BOVIN23455 | |||
| 562912 | DANRE37607 | |||
| 100030163 | MONDO33187 | |||
| 100146561 | HORSE05348 | |||
| 100386336 | CALJA04710 | |||
| 100458456 | PONAB02338 | |||
| 100481909 | AILME15429 | |||
| 100490885 | Xenbase:XB-GENE-6050660 |
