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MIRAGE
ADAM metallopeptidase with thrombospondin type 1 motif 15
Summary
- Gene Symbol
-
- ADAMTS15
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8TE58 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| myoblast fusion | ||
| extracellular matrix disassembly | ||
| extracellular matrix organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| cell surface | ||
| extracellular matrix | ||
| collagen-containing extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| endopeptidase activity | ||
| metalloendopeptidase activity | ||
| heparin binding | ||
| zinc ion binding | ||
| extracellular matrix binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Thrombospondin
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050646 | distal arthrogryposis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100064739 | HORSE40302 | ||
| 100082076 | ORNAN02447 | ||
| 100170087 | CIOIN02709 | ||
| 100220573 | TAEGU13938 | ||
| 100343187 | RABIT00448 | ||
| 100387523 | CALJA05801 | ||
| 100457224 | PONAB04231 | ||
| 100466459 | AILME19379 | ||
| 100518325 | PIGXX35797 | ||
| 100585753 | NOMLE10865 |
