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solute carrier family 8 (sodium/lithium/calcium exchanger), member B1

Summary

Gene Symbol

Slc8b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

170756

PubChem

170756

Alliance of Genome Resources

MGI:2180781

Annotation

Keyword

Alternative splicing
Antiport
Calcium transport
Cell membrane
Glycoprotein
Lithium
Mitochondrion inner membrane
Phosphoprotein
Reference proteome
Sensory transduction
Signal
Sodium transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q925Q3	Na(+)/K(+)/Ca(2+)-exchange protein 6 Sodium/calcium exchanger protein, mitochondrial Sodium/potassium/calcium exchanger 6 Solute carrier family 24 member 6 Solute carrier family 8 member B1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
mitochondrial calcium ion transmembrane transport	ISO
mitochondrial calcium ion transmembrane transport	IDA	20018762
mitochondrial calcium ion transmembrane transport	IMP	28445457
intracellular calcium ion homeostasis	IBA
sodium ion transmembrane transport	IDA	14625281

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

calcium ion transport [inference]

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

mitochondrial transport [inference]

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

mitochondrial calcium ion transmembrane transport

calcium export from the mitochondrion

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of lymphocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis

regulation of signaling [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of store-operated calcium entry

regulation of secretion [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of protein secretion [inference]

regulation of insulin secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion

regulation of peptide transport [inference]

regulation of peptide secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion

regulation of locomotion [inference]

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

regulation of lymphocyte chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of lymphocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

regulation of lymphocyte chemotaxis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol [inference]

calcium export from the mitochondrion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

regulation of insulin secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of protein secretion [inference]

regulation of insulin secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of leukocyte chemotaxis [inference]

regulation of lymphocyte chemotaxis

regulation of mononuclear cell migration [inference]

regulation of lymphocyte migration [inference]

regulation of lymphocyte chemotaxis

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

regulation of peptide hormone secretion [inference]

regulation of insulin secretion

regulation of membrane potential [inference]

regulation of cardiac muscle cell membrane potential

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IDA	20018762 24067497
mitochondrial inner membrane	ISO
plasma membrane	IDA	14625281
membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane

mitochondrial inner membrane

mitochondrial crista

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
calcium:sodium antiporter activity	ISO
calcium:sodium antiporter activity	IDA	14625281 20018762
calcium:sodium antiporter activity	IMP	28445457
calcium:sodium antiporter activity	IBA
identical protein binding	ISO