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trafficking kinesin protein 2

Summary

Gene Symbol

Trak2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

171086

PubChem

171086

Alliance of Genome Resources

RGD:620915

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
Endosome
Glycoprotein
Mitochondrion
Reference proteome
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6IP86
Q8R2H7	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein homolog GABA-A receptor-interacting factor 1 O-GlcNAc transferase-interacting protein of 98 kDa
A6IP87

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
regulation of transcription by RNA polymerase II	IDA	12435728
protein O-linked glycosylation	IDA	12435728
protein targeting	IDA	12435728
protein targeting	IBA
neurotransmitter transport	NAS	12034717

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle-mediated transport [inference]

endosome to lysosome transport

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrion distribution

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

establishment of localization [inference]

transport [inference]

neurotransmitter transport

vesicle-mediated transport [inference]

endosome to lysosome transport

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

establishment of protein localization [inference]

protein targeting

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle localization [inference]

mitochondrion localization [inference]

mitochondrion distribution

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport [inference]

endosome to lysosome transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde axonal transport of mitochondrion

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule [inference]

axonal transport of mitochondrion [inference]

anterograde axonal transport of mitochondrion

dendritic transport of mitochondrion

anterograde dendritic transport of mitochondrion

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

negative regulation of axonogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis

regulation of axonogenesis [inference]

negative regulation of axonogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	12034717 12435728
cytoplasm	IDA	12034717 19528298
mitochondrion	IDA	19528298
mitochondrion	IBA
mitochondrion	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

membrane [inference]

plasma membrane

site of polarized growth [inference]

growth cone [inference]

axonal growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

early endosome

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IPI	12034717
protein binding	IPI	12435728 19103291 19528298 24161670
myosin binding	IBA
kinesin binding	IDA	15644324
enzyme binding	IPI	12435728

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

GABA receptor binding

cytoskeletal protein binding [inference]

enzyme binding

protein domain specific binding [inference]

TPR domain binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

trafficking kinesin-binding protein

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
GABA receptor binding
anterograde axonal transport of mitochondrion
mitochondrion distribution
myosin binding
neurogenesis
protein targeting
vesicle transport along microtubule

Displaying **all 2** entries
InterPro
HAP1, N-terminal
Trafficking kinesin-binding protein, C-terminal

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
neuronal cell body	PMID:25653102
early endosome	PMID:17062640
dendrite	PMID:25653102
axonal growth cone	PMID:25653102

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements