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acid-sensing ion channel 3

Summary

Gene Symbol

Asic3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

171209

PubChem

171209

Alliance of Genome Resources

MGI:2159339

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoplasm
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Sodium channel
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6X1Y6	Amiloride-sensitive cation channel 3 Dorsal root ASIC

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of pain	IMP	11754838 12060708
establishment of localization in cell	IMP	19590043
enterobactin transport	IEA
sodium ion transport	ISO
detection of mechanical stimulus involved in sensory perception	IMP	11754838

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

response to stimulus [inference]

response to stress [inference]

response to heat

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

response to pH [inference]

response to acidic pH

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception

detection of chemical stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception

detection of chemical stimulus involved in sensory perception of pain

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception of pain [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron coordination entity transport [inference]

siderophore transport [inference]

enterobactin transport

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

enterobactin transport

organic hydroxy compound transport [inference]

enterobactin transport

establishment of localization in cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA ISO	11854527
perinuclear region of cytoplasm	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
enterobactin transmembrane transporter activity	IMP	19590043
ligand-gated sodium channel activity	IBA ISO
monoatomic cation channel activity	IDA IMP TAS	11754838 11854527

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

siderophore-iron transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

organic hydroxy compound transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

acid-sensing ion channel 3

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ligand-gated sodium channel activity
sodium channel activity
sodium ion transmembrane transport

Displaying **all 3** entries
InterPro
Epithelial sodium channel, chordates
Epithelial sodium channel, conserved site
Epithelial sodium channel

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9311		HGNC:101	HUMAN92062
Drosophila melanogaster	34299		FB:FBgn0065109
Drosophila melanogaster	37566		FB:FBgn0034730
Caenorhabditis elegans	171992		WB:WBGene00016066
Caenorhabditis elegans	182851		WB:WBGene00016063
Caenorhabditis elegans	182852		WB:WBGene00016064
Caenorhabditis elegans	184882		WB:WBGene00009073
Caenorhabditis elegans	185036		WB:WBGene00017879
Caenorhabditis elegans	189051		WB:WBGene00020903
Rattus norvegicus	286920	10116_1:0018ea	RGD:708578	RATNO29465