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calsyntenin 3

Summary

Gene Symbol

Clstn3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

171393

PubChem

171393

Alliance of Genome Resources

RGD:621153

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell membrane
Cell projection
Endoplasmic reticulum
Glycoprotein
Golgi apparatus
Lipid droplet
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8R553

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 25 in total

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GO Term	Evidence Code	PMID
regulation of presynapse assembly	IEA ISO
positive regulation of inhibitory synapse assembly	ISO ISS
adaptive thermogenesis	ISO ISS
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
positive regulation of lipid catabolic process	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

adaptive thermogenesis

cold-induced thermogenesis

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly

synapse organization [inference]

synapse assembly

export from cell [inference]

secretion by cell [inference]

protein secretion

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

motor learning

behavior [inference]

learning or memory [inference]

learning [inference]

motor learning

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

cold-induced thermogenesis

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

sympathetic neuron projection extension

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis [inference]

cold-induced thermogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

regulation of lipid catabolic process [inference]

positive regulation of lipid catabolic process

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of localization [inference]

regulation of lipid storage [inference]

negative regulation of lipid storage

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

positive regulation of protein localization to synapse

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

regulation of lipid localization [inference]

negative regulation of lipid localization [inference]

negative regulation of lipid storage

regulation of growth [inference]

regulation of cell growth

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid catabolic process

positive regulation of signaling [inference]

positive regulation of synaptic transmission

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of lipid localization [inference]

negative regulation of lipid storage

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

regulation of cellular component organization [inference]

regulation of cell growth

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

regulation of synapse organization [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of lipid droplet fusion

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of excitatory synapse assembly

negative regulation of excitatory synapse assembly

regulation of presynapse assembly

regulation of inhibitory synapse assembly [inference]

positive regulation of inhibitory synapse assembly

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to synapse [inference]

positive regulation of protein localization to synapse

positive regulation of protein localization [inference]

positive regulation of protein localization to synapse

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of excitatory synapse assembly

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of inhibitory synapse assembly

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
glutamatergic synapse	IEA ISO
endoplasmic reticulum	ISO
lipid droplet	ISO ISS
postsynaptic membrane	IBA IDA IEA ISO	12498782
dendrite	IEA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

lipid droplet

postsynaptic specialization [inference]

postsynaptic density

organelle membrane contact site

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell-cell adhesion mediator activity	IEA ISO ISS
amyloid-beta binding	IEA
kinesin binding	IEA
calcium ion binding	IEA
enzyme inhibitor activity	ISO ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

neurexin family protein binding

cytoskeletal protein binding [inference]

kinesin binding

X11-like protein binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
postsynaptic membrane	PMID:12498782

Ortholog

Displaying entries **21 - 30** of 89 in total

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Species	Gene ID	Orthologous MAtrix
Ornithorhynchus anatinus	100090989	ORNAN31116
Sarcophilus harrisii	100917446	SARHA04985
Callithrix jacchus	100387864	CALJA45068
Cercocebus atys	105583058	CERAT30011
Macaca fascicularis	102138603	MACFA02409
Macaca mulatta	715119	MACMU03421
Macaca nemestrina	105484224	MACNE35597
Papio anubis	101007125	PAPAN41901
Mandrillus leucophaeus	105541825	MANLE25337
Gorilla gorilla gorilla	101147547	GORGO05918

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Acknowledgements