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mannosidase 2, alpha B1

Summary

Gene Symbol

Man2b1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17159

PubChem

17159

Alliance of Genome Resources

MGI:107286

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Metal-binding
Reference proteome
Signal
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
O09159	Lysosomal acid alpha-mannosidase Mannosidase alpha class 2B member 1 Mannosidase alpha-B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
oligosaccharide catabolic process	IDA	9305783
protein modification process	IEA ISO
mannose metabolic process	IDA IMP	10400983 9305783 9355733
learning or memory	IMP	16014715

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

protein metabolic process [inference]

protein modification process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

macromolecule modification [inference]

protein modification process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

behavior [inference]

learning or memory

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lysosomal lumen	IDA	9305783
intracellular membrane-bounded organelle	ISO
nucleoplasm	IEA ISO
lysosome	IBA
extracellular space	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
mannose binding	IEA ISO
alpha-mannosidase activity	IBA IDA IMP ISO	10400983 9305783 9355733

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

alpha-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3413	alpha-mannosidosis	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 74 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pan troglodytes	455745		PANTR17293
Canis lupus familiaris	484932		CANLF07819
Felis catus	493697		FELCA03210
Danio rerio	541519	ZFIN:ZDB-GENE-050327-52	DANRE01910
Macaca mulatta	716173		MACMU20846
Macaca mulatta	716302		MACMU20846
Xenopus tropicalis	779924	Xenbase:XB-GENE-958698
Monodelphis domestica	100010377		MONDO18080
Pongo abelii	100174476		PONAB15778
Callithrix jacchus	100395073		CALJA23091

GlyTouCan

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Acknowledgements