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Protein Wnt-1

Summary

Gene Symbol

cwn-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

173399

PubChem

173399

Alliance of Genome Resources

WB:WBGene00000857

Annotation

Keyword

Cell membrane
Cytoplasm
Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Neurogenesis
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P34888

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
cell fate specification	IGI	19389360
neuron migration	IMP	18622031
neuron migration	IGI	18622031
multicellular organism development	IEA
nervous system development	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

neuron differentiation

cell fate commitment

cell motility [inference]

cell migration [inference]

neuron migration

neuroblast migration

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development

system development [inference]

nervous system development

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

neurogenesis [inference]

generation of neurons

neuron differentiation

cell fate commitment

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of neuron migration [inference]

regulation of motor neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

regulation of developmental process [inference]

regulation of vulval development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance [inference]

regulation of anterior/posterior axon guidance [inference]

positive regulation of anterior/posterior axon guidance

regulation of sensory neuron axon guidance [inference]

positive regulation of sensory neuron axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

regulation of neuron migration [inference]

regulation of motor neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of neuron migration [inference]

positive regulation of motor neuron migration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
cytoplasm	IEA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IEA
frizzled binding	ISS	7553861
frizzled binding	IBA
cytokine activity	IBA
receptor tyrosine kinase binding	IPI	17942487

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

receptor tyrosine kinase binding

receptor ligand activity

cytokine activity

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Wnt

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
canonical Wnt signaling pathway
cell fate commitment
cytokine activity
neuron differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Wnt protein, conserved site
Wnt, C-terminal domain
Wnt

Ortholog

Displaying entries **1 - 10** of 21 in total

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Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	7471	FB:FBgn0284084
Xenopus tropicalis	7472	Xenbase:XB-GENE-486595
Danio rerio	7482	ZFIN:ZDB-GENE-060824-6
Drosophila melanogaster	22408	FB:FBgn0284084
Xenopus tropicalis	22413	Xenbase:XB-GENE-486595
Danio rerio	22414	ZFIN:ZDB-GENE-060824-6
Homo sapiens	22416	HGNC:15983
Xenopus tropicalis	22417	Xenbase:XB-GENE-484098
Xenopus tropicalis	30123	Xenbase:XB-GENE-484098
Xenopus tropicalis	30127	Xenbase:XB-GENE-486595