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MIRAGE

Chitin synthase chs-2;chitin synthase

Summary

Gene Symbol

chs-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

173405

KEGG Gene ID

cel:CELE_F48A11.1

PubChem

173405

Alliance of Genome Resources

WB:WBGene00000497

Annotation

Keyword

Alternative splicing
Cell membrane
Coiled coil
Developmental protein
Glycoprotein
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0K3AR16
G5EBQ8	Chitin-UDP acetyl-glucosaminyl transferase chs-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
chitin biosynthetic process	IMP	16098962
chitin biosynthetic process	IBA
positive regulation of nematode larval development	IMP	16098962

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

amino sugar metabolic process [inference]

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

positive regulation of multicellular organismal process [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

regulation of multicellular organismal development [inference]

regulation of post-embryonic development [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

regulation of nematode larval development [inference]

positive regulation of nematode larval development

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

regulation of multicellular organismal development [inference]

regulation of post-embryonic development [inference]

positive regulation of post-embryonic development [inference]

positive regulation of nematode larval development

regulation of nematode larval development [inference]

positive regulation of nematode larval development

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA
cell septum
cell periphery

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
chitin synthase activity	ISS	11589574
chitin synthase activity	IBA
chitin synthase activity	IEA
glycosyltransferase activity	IEA
hexosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

hexosyltransferase activity

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitin synthase

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cell wall chitin biosynthetic process
chitin synthase activity
hexosyltransferase activity

Displaying **all 2** entries
InterPro
Chitin synthase
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00698

Name

chitin synthase [EC:2.4.1.16]

References

16098962

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06028	2.4.1.16	G97099AY	G97099AY

Rhea

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.16

PMID

Ortholog

Displaying entry **11 - 11** of 11 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	101886093	ZFIN:ZDB-GENE-060503-226

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Last updated: December 8, 2025