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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
alpha fetoprotein
Summary
- Gene Symbol
-
- AFP
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Copper
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Metal-binding
- Nickel
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Sulfation
- Proteins
| UniProt | Protein Name |
|---|---|
| P02771 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| apoptotic process | ||
| immune response | ||
| ovulation from ovarian follicle | ||
| progesterone metabolic process | ||
| homeostasis of number of cells |
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum lumen | ||
| extracellular space | ||
| cytoplasm |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| metal ion binding | ||
| small molecule binding |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- albumin
- Functional Category
-
- L: Replication, recombination and repair
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| protein transport within extracellular region |
| vitamin E binding |
| vitamin transport |
| InterPro |
|---|
| ALB/AFP/VDB |
| Serum albumin, N-terminal |
| Serum albumin, conserved site |
| Serum albumin-like |
| Serum albumin/Alpha-fetoprotein/Afamin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:1380 | endometrial cancer | |
| DOID:1883 | hepatitis C | |
| DOID:1911 | endodermal sinus tumor | |
| DOID:2237 | hepatitis | |
| DOID:3305 | teratocarcinoma | |
| DOID:3308 | embryonal carcinoma | |
| DOID:4450 | renal cell carcinoma | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11576 | MGI:87951 | MOUSE45530 | ||
| 24177 | RGD:2065 | RATNO08300 | ||
| 397586 | PIGXX33855 | |||
| 403551 | CANLF03483 | |||
| 461258 | 9598_0:0013cb | PANTR33768 | ||
| 506011 | BOVIN31652 | |||
| 704786 | MACMU35856 | |||
| 100023616 | MONDO25800 | |||
| 100034185 | HORSE31436 | |||
| 100345865 | RABIT05334 |
