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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Protein patched homolog 1;SSD domain-containing protein
Summary
- Gene Symbol
-
- ptc-1
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Glycoprotein
- Mitosis
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q09614 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell cycle | ||
| cell division | ||
| molting cycle, collagen and cuticulin-based cuticle | ||
| negative regulation of smoothened signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| hedgehog family protein binding | ||
| smoothened binding | ||
| hedgehog receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- patched
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hedgehog family protein binding |
| hedgehog receptor activity |
| smoothened binding |
| InterPro |
|---|
| Protein patched/dispatched |
| Sterol-sensing domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050860 | colorectal adenoma | |
| DOID:0050902 | medulloblastoma | |
| DOID:0070365 | nevoid basal cell carcinoma syndrome 1 | |
| DOID:0080016 | spina bifida | |
| DOID:0110876 | holoprosencephaly 7 | |
| DOID:10460 | nasopharyngitis | |
| DOID:10534 | stomach cancer | |
| DOID:12270 | coloboma | |
| DOID:1289 | neurodegenerative disease | |
| DOID:14330 | Parkinson's disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5727 | HGNC:9585 | |||
| 8643 | HGNC:9586 | |||
| 19206 | MGI:105373 | |||
| 19207 | MGI:1095405 | |||
| 30181 | ZFIN:ZDB-GENE-980526-44 | |||
| 30189 | ZFIN:ZDB-GENE-980526-196 | |||
| 35851 | FB:FBgn0003892 | |||
| 89830 | RGD:621425 | |||
| 6099106 | 6279_0:000ef5 | |||
| 6105810 | 6279_0:000eb6 |
