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Receptor-type tyrosine-protein phosphatase dep-1

Summary

Gene Symbol

dep-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

174437

PubChem

174437

Alliance of Genome Resources

WB:WBGene00009717

Annotation

Keyword

Alternative splicing
Glycoprotein
Protein phosphatase
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
G5EGJ9	Density-enhanced phosphatase homolog 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
vulval cell fate specification	IGI	28135265
axon guidance	IBA
protein dephosphorylation	IEA IMP	28135265
positive regulation of vulval development	IGI	28135265
signal transduction	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

developmental process [inference]

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of vulval development

regulation of developmental process [inference]

regulation of vulval development [inference]

positive regulation of vulval development

positive regulation of developmental process [inference]

positive regulation of vulval development

regulation of cellular process [inference]

signal transduction

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IBA IEA
phosphatase activity	IEA IMP	28135265
phosphoprotein phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor-type tyrosine-protein phosphatase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
dephosphorylation
protein tyrosine phosphatase activity

Displaying **all 5** entries
InterPro
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic
Protein-tyrosine phosphatase-like
Tyrosine-specific protein phosphatase, PTPase domain
Tyrosine-specific protein phosphatases domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 12 in total

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2

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DO ID	Disease Name	Source
DOID:0001816	angiosarcoma	Alliance of Genome Resources
DOID:0060108	brain glioma	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:1115	sarcoma	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources
DOID:3347	osteosarcoma	Alliance of Genome Resources
DOID:3498	pancreatic ductal adenocarcinoma	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:3963	thyroid gland carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 16 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	5787		HGNC:9665
Mus musculus	19263		MGI:97809
Drosophila melanogaster	31425		FB:FBgn0004368
Drosophila melanogaster	32115		FB:FBgn0004370
Rattus norvegicus	50677		RGD:62068
Rattus norvegicus	171125		RGD:620553
Rattus norvegicus	314843		RGD:1305922
Mus musculus	545902		MGI:3026877
Brugia malayi	6103290	6279_0:000d7a
Loa loa	9941281	7209_0:000f0a

GlyTouCan

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements