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malate dehydrogenase 1, NAD (soluble)

Summary

Gene Symbol

Mdh1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17449

PubChem

17449

Alliance of Genome Resources

MGI:97051

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
Methylation
NAD
Oxidoreductase
Phosphoprotein
Proteomics identification
Reference proteome
Tricarboxylic acid cycle
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P14152	Aromatic alpha-keto acid reductase Cytosolic malate dehydrogenase
A0A5F8MPN8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
malate metabolic process	IBA ISO
carboxylic acid metabolic process	IEA
NADH metabolic process	IBA ISO
NADP metabolic process	ISO
NAD metabolic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

tricarboxylic acid cycle

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

dicarboxylic acid metabolic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process [inference]

gluconeogenesis

hexose biosynthetic process [inference]

gluconeogenesis

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

dicarboxylic acid metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

hexose biosynthetic process [inference]

gluconeogenesis

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

glyceraldehyde-3-phosphate metabolic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NAD metabolic process

NADH metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytosol	IBA IDA ISO	5770240
cytoplasm	ISO
centrosome	ISO
myelin sheath	HDA	17634366
mitochondrion	HDA	18614015

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

microtubule organizing center [inference]

centrosome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
catalytic activity	IEA
hydroxyphenylpyruvate reductase activity
oxidoreductase activity	IEA
L-malate dehydrogenase activity	IBA IDA IMP ISO	5770240 7698769
diiodophenylpyruvate reductase activity	IEA

GO Hierarchy

molecular function

catalytic activity

oxidoreductase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

malate dehydrogenase activity

L-malate dehydrogenase activity

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112222	developmental and epileptic encephalopathy 88	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **111** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	179041	WB:WBGene00018491
Drosophila melanogaster	34414	FB:FBgn0262782
Callorhinchus milii	103177941		CALMI14184
Latimeria chalumnae	102357680		LATCH18020
Danio rerio	335715	ZFIN:ZDB-GENE-030131-7655	DANRE12103
Danio rerio	399662	ZFIN:ZDB-GENE-040204-1	DANRE18223
Astyanax mexicanus	103033607		ASTMX03263
Astyanax mexicanus	103036835		ASTMX11574
Ictalurus punctatus	108258652		ICTPU21472
Ictalurus punctatus	108269785		ICTPU35976

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Last updated: August 19, 2024