GlyCosmos Portal

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GO Term	Evidence Code	PMID
apical plasma membrane	IDA IEA	19741196
plasma membrane	IBA IEA
vacuolar proton-transporting V-type ATPase complex	IBA IPI	11441002
vacuolar proton-transporting V-type ATPase, V0 domain	IEA
apical part of cell	IDA	11441002

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex [inference]

vacuolar proton-transporting V-type ATPase complex

proton-transporting two-sector ATPase complex, proton-transporting domain [inference]

proton-transporting V-type ATPase, V0 domain

vacuolar proton-transporting V-type ATPase, V0 domain

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex [inference]

vacuolar proton-transporting V-type ATPase complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

apical part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
proton-transporting ATPase activity, rotational mechanism	IEA
ATPase binding	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

binding [inference]

protein binding [inference]

enzyme binding [inference]

ATPase binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATPase

Functional Category

C: Energy production and conversion
D: Cell cycle control, cell division, chromosome partitioning
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATPase binding
monoatomic ion transport
proton-transporting ATPase activity, rotational mechanism
vacuolar acidification

Displaying **all 2** entries
InterPro
ATPase, V0 complex, subunit 116kDa, eukaryotic
V-type ATPase, V0 complex, 116kDa subunit family

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
apical part of cell	PMID:11441002
vacuolar proton-transporting V-type ATPase complex	PMID:11441002

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0070134	autosomal recessive cutis laxa type IIA	Alliance of Genome Resources
DOID:0070390	developmental and epileptic encephalopathy 104	Alliance of Genome Resources
DOID:0110942	autosomal recessive osteopetrosis 1	Alliance of Genome Resources
DOID:0112171	wrinkly skin syndrome	Alliance of Genome Resources
DOID:14219	renal tubular acidosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 29 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	535	HGNC:865
Homo sapiens	10312	HGNC:11647
Mus musculus	11975	MGI:103286
Mus musculus	21871	MGI:104855
Homo sapiens	23545	HGNC:18481
Rattus norvegicus	29757	RGD:68405
Drosophila melanogaster	34587	FB:FBgn0032373
Drosophila melanogaster	42214	FB:FBgn0038613
Drosophila melanogaster	42216	FB:FBgn0028670
Drosophila melanogaster	43442	FB:FBgn0028671