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Basement membrane proteoglycan;Basement membrane-specific heparan sulfate proteoglycan core protein;Ig-like domain-containing protein

Summary

Gene Symbol

unc-52

Organism

Caenorhabditis elegans

External Links

NCBI Gene

175126

PubChem

175126

Alliance of Genome Resources

WB:WBGene00006787

Annotation

Keyword

Alternative splicing
Basement membrane
Cytoplasm
Disulfide bond
EGF-like domain
Immunoglobulin domain
Laminin EGF-like domain
Proteoglycan
Proteomics identification
Reference proteome
Repeat
Signal

Proteins

Displaying **all 10** entries
UniProt	Protein Name
H9G353
H9G354
G1K109
H9G348
H9G349
U4PS79
Q06561	Perlecan homolog Uncoordinated protein 52
H9G350
H9G351
H9G352

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
nematode larval development	IMP	21868609
mitochondrion organization	IMP	22253611
axon guidance
muscle organ development	IMP	7535716
fibroblast growth factor receptor signaling pathway	IGI	12654300

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly

cellular developmental process [inference]

cell differentiation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

myofibril assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

cell junction assembly [inference]

cell-substrate junction assembly [inference]

hemidesmosome assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

myofibril assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell junction assembly [inference]

cell-substrate junction assembly [inference]

hemidesmosome assembly

cell-substrate junction organization [inference]

cell-substrate junction assembly [inference]

hemidesmosome assembly

supramolecular fiber organization [inference]

myofibril assembly

multicellular organismal process [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

embryo development [inference]

embryo development ending in birth or egg hatching

post-embryonic development [inference]

larval development [inference]

nematode larval development

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

muscle organ morphogenesis

nematode pharyngeal gland morphogenesis

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

anatomical structure development [inference]

multicellular organism development [inference]

larval development [inference]

nematode larval development

embryo development [inference]

embryo development ending in birth or egg hatching

tissue development

animal organ development [inference]

muscle organ development

pharynx development [inference]

nematode pharynx development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell differentiation

locomotion

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of locomotion

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of multicellular organismal process [inference]

positive regulation of ovulation

positive regulation of reproductive process [inference]

positive regulation of ovulation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of striated muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of striated muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

regulation of supramolecular fiber organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of ovulation

regulation of ovulation [inference]

positive regulation of ovulation

regulation of reproductive process [inference]

regulation of ovulation [inference]

positive regulation of ovulation

positive regulation of reproductive process [inference]

positive regulation of ovulation

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
basement membrane	IDA	10512861 23283987 25692704 8393416
basement membrane	IEA
cytoplasm	IEA
extracellular matrix	IDA	8393416

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix [inference]

basement membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
structural molecule activity	ISS	8393416
extracellular matrix structural constituent	IMP	8393416
calcium ion binding	IEA

GO Hierarchy

molecular function

structural molecule activity

extracellular matrix structural constituent

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

laminin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
animal organ morphogenesis
tissue development

Displaying **all 5** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
EGF-like domain
Laminin G domain
Laminin IV
Laminin-type EGF domain

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	3339	Xenbase:XB-GENE-6465357
Xenopus tropicalis	15530	Xenbase:XB-GENE-6465357
Xenopus tropicalis	45320	Xenbase:XB-GENE-6465357
Xenopus tropicalis	175126	Xenbase:XB-GENE-6465357