GlyCosmos Portal

Submissions

inositol 1,4,5-triphosphate receptor associated 1

Summary

Gene Symbol

Irag1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17540

PubChem

17540

Alliance of Genome Resources

MGI:1338023

Annotation

Keyword

Alternative splicing
Coiled coil
Cytoplasm
Phosphoprotein
Proteomics identification
Reference proteome
Sarcoplasmic reticulum
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UR44
Q9WUX5	Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate JAW1-related protein MRVI1 Murine retrovirus integration site 1 protein Protein MRVI1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cGMP-mediated signaling	IMP	15483626
cGMP-mediated signaling	IBA
negative regulation of smooth muscle contraction	IMP	15483626
relaxation of vascular associated smooth muscle	IMP	15483626

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

cyclic-nucleotide-mediated signaling [inference]

cGMP-mediated signaling

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

relaxation of muscle [inference]

relaxation of smooth muscle [inference]

relaxation of vascular associated smooth muscle

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

relaxation of vascular associated smooth muscle

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

cyclic-nucleotide-mediated signaling [inference]

cGMP-mediated signaling

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction [inference]

negative regulation of smooth muscle contraction

relaxation of vascular associated smooth muscle

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

relaxation of vascular associated smooth muscle

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction

relaxation of vascular associated smooth muscle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
sarcoplasmic reticulum	IEA
perinuclear region of cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

sarcoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

sarcoplasmic reticulum

perinuclear region of cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	15483626

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

inositol 1,4,5-triphosphate receptor associated 1

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
MRVI1

Ortholog

Displaying entries **1 - 10** of 62 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	10335		HUMAN04636
Danio rerio	17540	ZFIN:ZDB-GENE-120221-4
Bos taurus	281918		BOVIN06763
Rattus norvegicus	308899		RATNO20883
Pan troglodytes	451025		PANTR02317
Macaca mulatta	702830		MACMU10236
Oryctolagus cuniculus	100008940		RABIT01064
Equus caballus	100071324		HORSE39106
Ornithorhynchus anatinus	100078702		ORNAN18818
Taeniopygia guttata	100226740		TAEGU26215