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MIRAGE
Polycystin cation channel PKD1/PKD2 domain-containing protein
Summary
- Gene Symbol
-
- cup-5
- Organism
- Caenorhabditis elegans
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosome organization | ||
| lysosomal transport | ||
| lysosomal lumen acidification | ||
| determination of adult lifespan | ||
| macromolecule catabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosome | ||
| lysosomal membrane | ||
| lysosomal membrane | ||
| endosome | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular ligand-gated monoatomic ion channel activity | ||
| monoatomic cation channel activity | ||
| calcium channel activity | ||
| NAADP-sensitive calcium-release channel activity | ||
| phosphatidylinositol-3,5-bisphosphate binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Mucolipin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| NAADP-sensitive calcium-release channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Mucolipin, extracytosolic domain |
| Mucolipin |
| Polycystin cation channel, PKD1/PKD2 |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080490 | mucolipidosis type IV |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 55283 | Xenbase:XB-GENE-980380 | ||
| 57192 | Xenbase:XB-GENE-982338 | ||
| 94178 | Xenbase:XB-GENE-982338 | ||
| 171166 | Xenbase:XB-GENE-980380 | ||
| 176074 | Xenbase:XB-GENE-982338 |
