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Integrin alpha pat-2

Summary

Gene Symbol

pat-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

176240

PubChem

176240

Alliance of Genome Resources

WB:WBGene00003929

Annotation

Keyword

Cell adhesion
Glycoprotein
Integrin
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P34446	Paralyzed arrest at two-fold protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
mitochondrion organization	IMP	22253611
cell adhesion	IEA
cell-matrix adhesion	IBA
integrin-mediated signaling pathway	IBA
integrin-mediated signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

developmental process [inference]

anatomical structure development [inference]

animal organ development

cellular developmental process [inference]

cell fate specification [inference]

vulval cell fate specification

homeostatic process [inference]

cellular homeostasis [inference]

muscle cell cellular homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of locomotion [inference]

positive regulation of locomotion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of distal tip cell migration

positive regulation of biological process [inference]

positive regulation of locomotion

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of vulval development

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of striated muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of ERBB signaling pathway [inference]

regulation of epidermal growth factor receptor signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

regulation of striated muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of striated muscle cell differentiation [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of epidermal growth factor receptor signaling pathway

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of sarcomere organization

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of supramolecular fiber organization [inference]

regulation of sarcomere organization [inference]

positive regulation of sarcomere organization

positive regulation of supramolecular fiber organization [inference]

positive regulation of sarcomere organization

regulation of membrane invagination [inference]

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of membrane invagination [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of phagocytosis, engulfment [inference]

positive regulation of phagocytosis, engulfment [inference]

positive regulation of engulfment of apoptotic cell

regulation of engulfment of apoptotic cell [inference]

positive regulation of engulfment of apoptotic cell

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance [inference]

positive regulation of engulfment of apoptotic cell

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of distal tip cell migration

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
integrin complex	ISS
integrin complex	IBA
integrin complex	IEA
external side of plasma membrane	IBA
cell surface	IDA	22615577

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical entity [inference]

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IDA	22615577
integrin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Integrin

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 5** entries
Gene Ontology
angiogenesis
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 5** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha, N-terminal
Integrin alpha, third immunoglobulin-like domain
Integrin domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
Z disc	PMID:22615577
basement membrane	PMID:31387941
M band	PMID:22615577
integrin complex	PMID:31387941

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements