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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Microsomal triglyceride transfer protein homolog
Summary
- Gene Symbol
-
- dsc-4
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Endoplasmic reticulum
- Lipid transport
- Lipid-binding
- Reference proteome
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| G5ECG7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| phospholipid transport | ||
| plasma lipoprotein particle assembly | ||
| lipoprotein transport | ||
| IRE1-mediated unfolded protein response | ||
| cellular component organization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| endoplasmic reticulum | ||
| basolateral plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| phospholipid transporter activity | ||
| lipid binding | ||
| lipid transfer activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Microsomal triglyceride transfer protein
- Functional Category
-
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| lipid binding |
| lipid transport |
| lipid transporter activity |
| lipoprotein metabolic process |
| phospholipid transport |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:10763 | hypertension | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:13810 | familial hypercholesterolemia | |
| DOID:1386 | abetalipoproteinemia | |
| DOID:2018 | hyperinsulinism | |
| DOID:9452 | steatotic liver disease | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 4547 | HGNC:7467 | |||
| 17777 | MGI:106926 | |||
| 35362 | FB:FBgn0266369 | |||
| 310900 | RGD:1308388 | |||
| 406207 | ZFIN:ZDB-GENE-040419-2 | |||
| 9947360 | 7209_0:003299 | |||
| 25343605 | 51031_0:002c32 | |||
| 25343607 | 51031_0:002c2c | |||
| 36381265 | 34506_0:0011eb | |||
| 66059843 | 6279_0:002464 |
