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Microsomal triglyceride transfer protein homolog

Summary

Gene Symbol

dsc-4

Organism

Caenorhabditis elegans

External Links

NCBI Gene

176852

PubChem

176852

Alliance of Genome Resources

WB:WBGene00001099

Annotation

Keyword

Endoplasmic reticulum
Lipid transport
Lipid-binding
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
G5ECG7	Defecation suppressor of clk-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
lipid transport	IEA
phospholipid transport	IEA
endoplasmic reticulum unfolded protein response	HEP	12186849
macromolecule localization	IEA
plasma lipoprotein particle assembly	IDA	17924655

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

localization [inference]

macromolecule localization

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

phospholipid transport

protein transport [inference]

lipoprotein transport

organophosphate ester transport [inference]

phospholipid transport

nitrogen compound transport [inference]

protein transport [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

lipoprotein localization [inference]

lipoprotein transport

establishment of protein localization [inference]

protein transport [inference]

lipoprotein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

IRE1-mediated unfolded protein response

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IDA	17924655
endoplasmic reticulum	IBA
endoplasmic reticulum	IEA
Golgi apparatus	IBA
basolateral plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

basolateral plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phospholipid transporter activity	IBA
phospholipid transporter activity	IEA
lipid binding	IEA
lipid transfer activity	ISS	14657502

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Microsomal triglyceride transfer protein

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
lipid binding
lipid transport
lipid transporter activity
lipoprotein metabolic process
phospholipid transport

Displaying **all 6** entries
InterPro
Lipid transport protein, beta-sheet shell
Lipovitellin-phosvitin complex, superhelical domain
MTP large subunit, lipid-binding domain
Microsomal triglyceride transfer protein large subunit
Vitellinogen, beta-sheet N-terminal
Vitellogenin, N-terminal