GlyCosmos Portal

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GO Term	Evidence Code	PMID
ABC-type transporter activity	IEA
ATP hydrolysis activity	IEA
ATPase-coupled transmembrane transporter activity	IBA
ABC-type xenobiotic transporter activity	IEA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

efflux transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
apical plasma membrane	PMID:26057124
membrane	PMID:7743993

Disease

Disease Ontology

Displaying entries **11 - 20** of 52 in total

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DO ID	Disease Name	Source
DOID:0110893	inflammatory bowel disease 13	Alliance of Genome Resources
DOID:10159	osteonecrosis	Alliance of Genome Resources
DOID:10939	antisocial personality disorder	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:12236	primary biliary cholangitis	Alliance of Genome Resources
DOID:12365	malaria	Alliance of Genome Resources
DOID:13241	Behcet's disease	Alliance of Genome Resources
DOID:13413	hepatic encephalopathy	Alliance of Genome Resources
DOID:13580	cholestasis	Alliance of Genome Resources
DOID:1485	cystic fibrosis	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 26** of 26 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Necator americanus	25348981	51031_0:001986
Necator americanus	25357086	51031_0:000a64
Necator americanus	25357087	51031_0:000a65
Strongyloides ratti	36373715	34506_0:002f21
Danio rerio	100136865		ZFIN:ZDB-GENE-080204-52
Xenopus tropicalis	100494740		Xenbase:XB-GENE-950725