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dynein cytoplasmic 1 light intermediate chain 2

Summary

Gene Symbol

DYNC1LI2

Organism

Homo sapiens (human)

External Links

NCBI Gene

1783

PubChem

1783

Alliance of Genome Resources

HGNC:2966

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cytoskeleton
Dynein
Methylation
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
O43237	Dynein light intermediate chain 2, cytosolic LIC53/55

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IBA
microtubule-based movement	IBA
centrosome localization	IEA
cellular response to nerve growth factor stimulus	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to nerve growth factor [inference]

cellular response to nerve growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

localization [inference]

microtubule organizing center localization [inference]

centrosome localization

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
kinetochore	IEA
late endosome	IEA
centrosome	IDA	21399614
cytosol	TAS
cytoplasmic dynein complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex

cytoplasmic dynein complex

catalytic complex [inference]

dynein complex

cytoplasmic dynein complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATP binding	IEA
identical protein binding	IEA
dynein heavy chain binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytoplasmic dynein 1 light intermediate chain 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein heavy chain binding
microtubule cytoskeleton organization
microtubule-based movement
nucleotide binding

Displaying **all 3** entries
InterPro
Dynein 1 light intermediate chain
Dynein family light intermediate chain
P-loop containing nucleoside triphosphate hydrolase

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements