DNA methyltransferase 1
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| DNA methylation-dependent heterochromatin formation | ||
| transcription, DNA-templated | ||
| DNA-templated transcription | ||
| positive regulation of gene expression |
| GO Term | Evidence Code | PMID |
|---|---|---|
| female germ cell nucleus | ||
| nucleus | ||
| nucleus | ||
| nucleoplasm | ||
| replication fork |
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| DNA binding | ||
| DNA (cytosine-5-)-methyltransferase activity | ||
| DNA (cytosine-5-)-methyltransferase activity | ||
| protein binding |
| Gene Ontology |
|---|
| chromatin binding |
| methylation |
| transferase activity |
| zinc ion binding |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050548 | hereditary sensory neuropathy | |
| DOID:0050968 | autosomal dominant cerebellar ataxia, deafness and narcolepsy | |
| DOID:0070158 | hereditary sensory neuropathy type 1E | |
| DOID:12361 | Graves' disease | |
| DOID:3908 | lung non-small cell carcinoma |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025