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Kunitz/Bovine pancreatic trypsin inhibitor domain protein

Summary

Gene Symbol

mec-9

Organism

Caenorhabditis elegans

External Links

NCBI Gene

179382

PubChem

179382

Alliance of Genome Resources

WB:WBGene00003173

Annotation

Keyword

Disulfide bond
EGF-like domain
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G3MVG9
Q18761

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
detection of mechanical stimulus involved in sensory perception of touch	IGI	8692859
positive regulation of mechanosensory behavior	IGI	8692859
mechanosensory behavior	IGI IMP	8562083 8692859
response to mechanical stimulus	IMP	8562083
positive regulation of detection of mechanical stimulus involved in sensory perception of touch	IGI	8692859

GO Hierarchy

biological process

multicellular organismal process [inference]

behavior [inference]

mechanosensory behavior

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to abiotic stimulus [inference]

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of touch

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of detection of mechanical stimulus involved in sensory perception of touch

positive regulation of behavior [inference]

positive regulation of mechanosensory behavior

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

regulation of detection of mechanical stimulus involved in sensory perception of touch [inference]

positive regulation of detection of mechanical stimulus involved in sensory perception of touch

regulation of mechanosensory behavior [inference]

positive regulation of mechanosensory behavior

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of detection of mechanical stimulus involved in sensory perception of touch

regulation of sensory perception [inference]

regulation of detection of mechanical stimulus involved in sensory perception of touch [inference]

positive regulation of detection of mechanical stimulus involved in sensory perception of touch

regulation of behavior [inference]

positive regulation of behavior [inference]

positive regulation of mechanosensory behavior

regulation of mechanosensory behavior [inference]

positive regulation of mechanosensory behavior

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of detection of mechanical stimulus involved in sensory perception of touch

positive regulation of behavior [inference]

positive regulation of mechanosensory behavior

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	TAS	8562083

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase inhibitor activity	IEA
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

EGF-like domain

Functional Category

H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
calcium ion binding
serine-type endopeptidase inhibitor activity

Displaying **all 6** entries
InterPro
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site
Pancreatic trypsin inhibitor Kunitz domain superfamily
Pancreatic trypsin inhibitor Kunitz domain

Ortholog

Displaying **all 4** entries
Species	Gene ID	OrthoDB
Brugia malayi	6105113	6279_0:001bf4
Necator americanus	25355088	51031_0:004445
Necator americanus	25355089	51031_0:004443
Strongyloides ratti	36373462	34506_0:002d7b