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Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

gly-20

Organism

Caenorhabditis elegans

External Links

NCBI Gene

179562

KEGG Gene ID

cel:CELE_C03E10.4

PubChem

179562

Alliance of Genome Resources

WB:WBGene00001645

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Proteomics identification
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O17560	Beta-1,2-N-acetylglucosaminyltransferase II GlcNAc-T II Mannoside acetylglucosaminyltransferase 2 N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
oligosaccharide biosynthetic process	IEA
protein glycosylation	IEA
protein N-linked glycosylation	IBA IMP	22485160

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation

protein N-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA
Golgi apparatus	IEA
Golgi stack	IEA
Golgi membrane	IBA IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi stack

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	IBA IEA
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
metal ion binding
oligosaccharide biosynthetic process
protein N-linked glycosylation
transferase activity

Displaying **all 2** entries
InterPro
N-acetylglucosaminyltransferase II
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00736

Name

alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143]

References

2952645

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05985	2.4.1.143	G61751GZ	G39213VZ

Rhea

RHEA:12941

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.143

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0070253	congenital disorder of glycosylation type IIa	Alliance of Genome Resources
DOID:2978	carbohydrate metabolic disorder	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008019
Gene Name: Protein GLY-20

Ortholog

Displaying entries **1 - 10** of 11 in total

1

2

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	4247		HGNC:7045
Drosophila melanogaster	43563		FB:FBgn0039738
Rattus norvegicus	94273		RGD:620098
Mus musculus	217664		MGI:2384966
Xenopus tropicalis	448439		Xenbase:XB-GENE-978789
Brugia malayi	6102728	6279_0:002600
Loa loa	9940316	7209_0:000b7d
Necator americanus	25347579	51031_0:001044
Strongyloides ratti	36384558	34506_0:002857
Danio rerio	100000478		ZFIN:ZDB-GENE-070410-54

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements