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diphthamide biosynthesis 2

Summary

Gene Symbol

DPH2

Organism

Homo sapiens (human)

External Links

NCBI Gene

1802

PubChem

1802

Alliance of Genome Resources

HGNC:3004

JoGo

DPH2

TogoVar

DPH2

Annotation

Keyword

Acetylation
Alternative splicing
Disease variant
Dwarfism
Ectodermal dysplasia
Hypotrichosis
Intellectual disability
Iron-sulfur
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B3KRB8
Q9BQC3	Diphthamide biosynthesis protein 2 Diphtheria toxin resistance protein 2 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein histidyl modification to diphthamide	ISS
protein histidyl modification to diphthamide	TAS
protein histidyl modification to diphthamide	IMP	32576952
protein histidyl modification to diphthamide	IBA
protein histidyl modification to diphthamide	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-histidine modification [inference]

protein histidyl modification to diphthamide

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183
metal ion binding	IEA
4 iron, 4 sulfur cluster binding	ISS
2-(3-amino-3-carboxypropyl)histidine synthase activity	ISS
2-(3-amino-3-carboxypropyl)histidine synthase activity	EXP	20559380