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dipeptidyl peptidase like 6
Summary
- Gene Symbol
-
- DPP6
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Aminopeptidase
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Intellectual disability
- Neurodegeneration
- Proteomics identification
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8IYG9 |
|
| E9PF59 |
|
| A7E2E4 |
|
| E9PDL2 |
|
| P42658 |
|
| B7Z299 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| protein localization to plasma membrane | ||
| regulation of potassium ion transmembrane transport | ||
| regulation of potassium ion transmembrane transport | ||
| regulation of potassium ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| voltage-gated potassium channel complex | ||
| voltage-gated potassium channel complex | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| serine-type peptidase activity | ||
| dipeptidyl-peptidase activity | ||
| potassium channel regulator activity | ||
| potassium channel regulator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- peptidase
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| dipeptidyl-peptidase activity |
| proteolysis |
| serine-type peptidase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Dipeptidylpeptidase IV, N-terminal domain |
| Peptidase S9, prolyl oligopeptidase, catalytic domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070063 | autosomal dominant intellectual developmental disorder 33 | |
| DOID:12377 | spinal muscular atrophy | |
| DOID:332 | amyotrophic lateral sclerosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 1803 | FB:FBgn0259175 | ||
| 1804 | Xenbase:XB-GENE-999312 | ||
| 2191 | SGD:S000005745 | ||
| 13482 | FB:FBgn0259175 | ||
| 13483 | Xenbase:XB-GENE-999312 | MOUSE45634 | |
| 14089 | SGD:S000005745 | ||
| 25253 | SGD:S000005745 | ||
| 29272 | Xenbase:XB-GENE-999312 | RATNO30946 | |
| 57628 | SGD:S000005745 | ||
| 180042 | Xenbase:XB-GENE-999312 |
