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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

dihydropyrimidinase like 3

Summary

Gene Symbol

DPYSL3

Organism

Homo sapiens (human)

External Links

NCBI Gene

1809

PubChem

1809

Alliance of Genome Resources

HGNC:3015

Annotation

Keyword

3D-structure
Alternative splicing
Cell projection
Cytoplasm
Direct protein sequencing
Phosphoprotein
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q6DEN2
Q14195	Collapsin response mediator protein 4 Unc-33-like phosphoprotein 1
Q8IXW6
A0A140VK07

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
cellular response to cytokine stimulus	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular developmental process [inference]

cell development [inference]

neuron development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin crosslink formation

actin filament bundle organization [inference]

actin filament bundle assembly

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

neuron development

cellular developmental process [inference]

cell development [inference]

neuron development

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

response to axon injury

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
extracellular space	ISS
cytosol	ISS
cytosol	TAS
cytosol	IBA
lamellipodium	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

filamentous actin

cellular anatomical entity [inference]

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

cell body

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
dihydropyrimidinase activity	IBA
protein binding	IPI	21044950 25416956 28514442 29892012 31515488 32296183 33961781
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IBA
SH3 domain binding	ISS
filamin binding	IPI	25358863

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

dihydropyrimidinase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

filamin binding

protein domain specific binding [inference]

SH3 domain binding

identical protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

chondroitin sulfate binding

sulfur compound binding [inference]

chondroitin sulfate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dihydropyrimidinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity

Displaying **all 3** entries
InterPro
Amidohydrolase-related
Metal-dependent hydrolase, composite domain superfamily
Metal-dependent hydrolase

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	1400	SGD:S000001466
Saccharomyces cerevisiae S288C	1808	SGD:S000001466
Xenopus tropicalis	1809	Xenbase:XB-GENE-944729
Saccharomyces cerevisiae S288C	10570	SGD:S000001466
Saccharomyces cerevisiae S288C	12933	SGD:S000001466
Saccharomyces cerevisiae S288C	12934	SGD:S000001466
Mus musculus	22240	Xenbase:XB-GENE-944729	MOUSE24121
Saccharomyces cerevisiae S288C	25416	SGD:S000001466
Saccharomyces cerevisiae S288C	25417	SGD:S000001466
Rattus norvegicus	25418	Xenbase:XB-GENE-944729	RATNO13486

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Last updated: April 7, 2025