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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

dihydropyrimidinase like 3

Summary

Gene Symbol

DPYSL3

Organism

Homo sapiens (human)

External Links

NCBI Gene

1809

PubChem

1809

Alliance of Genome Resources

HGNC:3015

Annotation

Keyword

3D-structure
Alternative splicing
Cell projection
Cytoplasm
Direct protein sequencing
Phosphoprotein
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q6DEN2
Q14195	Collapsin response mediator protein 4 Unc-33-like phosphoprotein 1
Q8IXW6
A0A140VK07

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
cellular response to cytokine stimulus	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

organonitrogen compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular catabolic process [inference]

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process

cellular developmental process [inference]

cell development [inference]

neuron development

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin crosslink formation

actin filament bundle organization [inference]

actin filament bundle assembly

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

neuron development

cellular developmental process [inference]

cell development [inference]

neuron development

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

response to axon injury

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of biological process [inference]

negative regulation of locomotion [inference]

negative regulation of cell motility [inference]

negative regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of cell motility [inference]

negative regulation of cell migration

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of filopodium assembly [inference]

positive regulation of filopodium assembly

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of filopodium assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

negative regulation of cell migration

negative regulation of cell motility [inference]

negative regulation of cell migration

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
growth cone	ISS
filamentous actin	ISS
cell body	ISS
synapse	IEA
exocytic vesicle	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

filamentous actin

cellular anatomical entity [inference]

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle

secretory vesicle [inference]

exocytic vesicle

cell body

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
dihydropyrimidinase activity	IBA
protein binding	IPI	21044950 25416956 28514442 29892012 31515488 32296183 33961781
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	IBA
SH3 domain binding	ISS
filamin binding	IPI	25358863

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

dihydropyrimidinase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

filamin binding

protein domain specific binding [inference]

SH3 domain binding

identical protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

chondroitin sulfate binding

sulfur compound binding [inference]

chondroitin sulfate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dihydropyrimidinase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity

Displaying **all 3** entries
InterPro
Amidohydrolase-related
Metal-dependent hydrolase, composite domain superfamily
Metal-dependent hydrolase

Ortholog

Displaying entries **51 - 60** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pelodiscus sinensis	102458374		PELSI04256
Callorhinchus milii	103177290		CALMI12759
Chlorocebus sabaeus	103244752		CHLSB11080
Ursus maritimus	103663689		URSMA04652
Nannospalax galili	103727394		NANGA03155
Serinus canaria	103817542		SERCA12608
Rhinopithecus roxellana	104678158		RHIRO26139
Pteropus vampyrus	105297062		PTEVA05865
Macaca nemestrina	105466915		MACNE08125
Mandrillus leucophaeus	105538914		MANLE36160

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Last updated: March 31, 2025