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EGF-like domain-containing protein;Ig-like domain-containing protein

Summary

Gene Symbol

him-4

Organism

Caenorhabditis elegans

External Links

NCBI Gene

181187

PubChem

181187

Alliance of Genome Resources

WB:WBGene00001863

Annotation

Keyword

Coiled coil
Disulfide bond
EGF-like domain
Glycoprotein
Immunoglobulin domain
Lectin
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 6** entries
UniProt	Protein Name
A4UVK0
G5EDG4
G5EG33
G5ED27
A0A4V0IK01
A0A4V0ILL2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
homophilic cell adhesion via plasma membrane adhesion molecules	IBA
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
basement membrane disassembly	IMP	15960981
basement membrane disassembly	IGI	15960981
basement membrane organization	IMP	25443298

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly [inference]

basement membrane disassembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly [inference]

basement membrane disassembly

basement membrane organization

basement membrane disassembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly [inference]

basement membrane disassembly

basement membrane organization

basement membrane disassembly

Displaying **all 4** entries
GO Term	Evidence Code	PMID
basement membrane	IDA	15960981
cytoplasm	IEA
adherens junction	IBA
extracellular matrix	IDA	25443298

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix [inference]

basement membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular matrix structural constituent	IMP	25443298
calcium ion binding	IEA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

inactive tyrosine-protein kinase 7

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold