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Zinc metalloproteinase nas-37

Summary

Gene Symbol

nas-37

Organism

Caenorhabditis elegans

External Links

NCBI Gene

181208

PubChem

181208

Alliance of Genome Resources

WB:WBGene00003553

Annotation

Keyword

Alternative splicing
Cleavage on pair of basic residues
Developmental protein
Disulfide bond
EGF-like domain
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Secreted
Signal
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q93243	Nematode astacin 37

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
ecdysis, collagen and cuticulin-based cuticle	IMP	15539494
molting cycle, collagen and cuticulin-based cuticle	IEA IMP	15255192
collagen and cuticulin-based cuticle development	IMP	15539494

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

multicellular organismal process [inference]

molting cycle process [inference]

ecdysis, collagen and cuticulin-based cuticle

molting cycle [inference]

molting cycle, collagen and cuticulin-based cuticle

developmental process [inference]

anatomical structure development [inference]

cuticle development [inference]

collagen and cuticulin-based cuticle development

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	IDA IEA	15539494

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 4** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA
metal ion binding	IEA
metalloendopeptidase activity	IBA IDA IEA	15539494
metallopeptidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tolloid

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
calcium ion binding
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding

Displaying **all 3** entries
InterPro
CUB domain
Peptidase M12A
Spermadhesin, CUB domain superfamily

Ortholog

Displaying entries **1 - 10** of 13 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila melanogaster	41815		FB:FBgn0038285
Danio rerio	327586		ZFIN:ZDB-GENE-030131-5797
Danio rerio	553530		ZFIN:ZDB-GENE-041001-209
Danio rerio	565535		ZFIN:ZDB-GENE-041001-208
Brugia malayi	6095692	6279_0:002172
Loa loa	9938368	7209_0:000a3e
Loa loa	9938369	7209_0:000a2f
Necator americanus	25350940	51031_0:0025e2
Necator americanus	25356730	51031_0:000680
Strongyloides ratti	36375347	34506_0:000b1f