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MIRAGE

Multidrug resistance-associated protein 5

Summary

Gene Symbol

mrp-5

Organism

Caenorhabditis elegans

External Links

NCBI Gene

181587

KEGG Gene ID

PubChem

181587

Alliance of Genome Resources

WB:WBGene00003411

Annotation

Keyword

ATP-binding
Cell membrane
Glycoprotein
Reference proteome
Repeat
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
G5EE72	ATP-binding cassette sub-family C member mrp-5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cobalamin transport	IMP
transmembrane transport	IBA
transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

cobalamin transport

transmembrane transport

nitrogen compound transport [inference]

cobalamin transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IBA
membrane	IEA
basolateral plasma membrane	EXP
basolateral plasma membrane	IC
basolateral plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

plasma membrane region [inference]

basolateral plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ATP binding	IEA
ABC-type vitamin B12 transporter activity	IMP
ATP hydrolysis activity	IEA
ABC-type transporter activity	IBA
ABC-type transporter activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type vitamin B12 transporter activity

vitamin transmembrane transporter activity [inference]

ABC-type vitamin B12 transporter activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

ABC-type vitamin B12 transporter activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
basolateral plasma membrane	PMID:24836561
intracellular organelle	PMID:24836561
nucleus	PMID:11997343

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	85320	HGNC:14639
Homo sapiens	10057	HGNC:56
Homo sapiens	94160	HGNC:14640
Mus musculus	244562	MGI:2441679
Mus musculus	27416	MGI:1351644
Rattus norvegicus	116721	RGD:70913
Rattus norvegicus	291923	RGD:735100

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026