sequestosome 1

Summary
Gene Symbol
  • Sqstm1
Organism
Mus musculus (house mouse)
NCBI Gene
18412
PubChem
18412
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Apoptosis
  • Autophagy
  • Cytoplasm
  • Cytoplasmic vesicle
  • Differentiation
  • Endoplasmic reticulum
  • Endosome
  • Immunity
  • Isopeptide bond
  • Lysosome
  • Nucleus
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Ubl conjugation
  • Zinc-finger
Proteins
Displaying 1 entry
UniProt Protein Name
Q64337
  • STONE14
  • Ubiquitin-binding protein p62
Gene Ontology (GO)
Displaying entries 1 - 5 of 53 in total
GO Term Evidence Code PMID
negative regulation of transcription by RNA polymerase II
mitophagy
mitophagy
mitophagy
pexophagy
GO Hierarchy
Displaying entries 1 - 5 of 31 in total
GO Term Evidence Code PMID
phagophore assembly site
P-body
P-body
cytoplasm
mitochondrion
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
ZZ-type domain-containing protein
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • K: Transcription
  • Q: Secondary metabolites biosynthesis, transport and catabolism
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:5408 Paget's disease of bone

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025