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MIRAGE
pregnancy-associated plasma protein A

Summary
Gene Symbol
  • Pappa
Organism
Mus musculus (house mouse)
NCBI Gene
18491
PubChem
18491
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Sushi
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
Q8R4K8
  • Insulin-like growth factor-dependent IGF-binding protein 4 protease
  • Pregnancy-associated plasma protein A
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
cell surface receptor signaling pathway
female pregnancy
protein catabolic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
pappalysin-1
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
Displaying all 4 entries
Gene Ontology
cell surface receptor signaling pathway
metalloendopeptidase activity
metallopeptidase activity
proteolysis
Displaying all 9 entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
LamG-like jellyroll fold
Metallopeptidase, catalytic domain superfamily
Myxococcus cysteine-rich repeat
Notch domain
Pappalysin-1/2
Peptidase M43, pregnancy-associated plasma-A
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily
Ortholog
Displaying entries 1 - 10 of 70 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
5069 Xenbase:XB-GENE-482885 HUMAN98178
18491 Xenbase:XB-GENE-482885
282647 BOVIN35196
313262 RATNO33990
443157 SHEEP08674
464690 PANTR44683
481692 CANLF02479
706783 MACMU13317
100014138 MONDO01673
100033920 HORSE24455
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025