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protocadherin 8

Summary

Gene Symbol

Pcdh8

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18530

PubChem

18530

Alliance of Genome Resources

MGI:1306800

Annotation

Keyword

Alternative splicing
Calcium
Cell adhesion
Cell membrane
Cell projection
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TSK3	Arcadlin Paraxial protocadherin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
somitogenesis	IMP	12591245
cell adhesion	IBA
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
chemical synaptic transmission	ISO
chemical synaptic transmission	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification [inference]

somitogenesis

segmentation [inference]

somitogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium

anatomical structure formation involved in morphogenesis [inference]

somitogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of synaptic membrane adhesion

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synaptic membrane adhesion

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GO Term	Evidence Code	PMID
plasma membrane	ISS	9787079
plasma membrane	IBA
dendrite	IEA
presynaptic membrane	IEA
synapse	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying 1 entry
GO Term	Evidence Code	PMID
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protocadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 4** entries
InterPro
Cadherin conserved site
Cadherin, N-terminal
Cadherin-like superfamily
Cadherin-like

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5100	Xenbase:XB-GENE-11536541	HUMAN17219
Caenorhabditis elegans	12936	WB:WBGene00000402
Caenorhabditis elegans	12939	WB:WBGene00000402
Caenorhabditis elegans	12943	WB:WBGene00000402
Xenopus tropicalis	18530	Xenbase:XB-GENE-11536541
Caenorhabditis elegans	53601	WB:WBGene00000402
Rattus norvegicus	64865	Xenbase:XB-GENE-11536541	RATNO09880
Caenorhabditis elegans	73173	WB:WBGene00000402
Caenorhabditis elegans	93699	WB:WBGene00000402
Caenorhabditis elegans	93700	WB:WBGene00000402