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MIRAGE

pericentriolar material 1

Summary

Gene Symbol

Pcm1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18536

PubChem

18536

Alliance of Genome Resources

MGI:1277958

Annotation

Keyword

Acetylation
Alternative splicing
Cell projection
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9R0L6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
neuron migration	IMP	18762586
centrosome cycle	ISO
centrosome cycle	IEA
interkinetic nuclear migration	IMP	20152126
cytoplasmic microtubule organization	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

microtubule anchoring

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

microtubule-based movement [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

microtubule organizing center organization [inference]

centrosome cycle

cell cycle process [inference]

centrosome cycle

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

cytoplasmic microtubule organization

microtubule anchoring

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

cilium organization [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

organelle assembly [inference]

cilium assembly

non-motile cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

non-motile cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

non-motile cilium assembly

microtubule organizing center organization [inference]

centrosome cycle

supramolecular fiber organization [inference]

cytoplasmic microtubule organization

multicellular organismal process [inference]

behavior [inference]

social behavior

stem cell population maintenance [inference]

neuronal stem cell population maintenance

developmental process [inference]

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

localization [inference]

protein-containing complex localization [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

protein-containing complex localization to centriolar satellite

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

microtubule-based transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

establishment of organelle localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

organelle localization [inference]

nucleus localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

establishment of organelle localization [inference]

nuclear migration [inference]

interkinetic nuclear migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration [inference]

interkinetic nuclear migration

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

intraciliary transport [inference]

intraciliary transport involved in cilium assembly

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle

protein localization to cytoskeleton [inference]

protein localization to microtubule cytoskeleton [inference]

protein localization to microtubule organizing center [inference]

protein localization to centrosome

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of cellular process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of neurogenesis [inference]

negative regulation of neurogenesis

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis

negative regulation of nervous system development [inference]

negative regulation of neurogenesis

regulation of biological quality [inference]

regulation of protein complex stability

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
pericentriolar material	IDA	20152126 23533177
nucleoplasm	ISO
nucleoplasm	IEA
cytoplasm	IDA	10579718 12571289
centrosome	ISO	24421332

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

cytosol

membrane [inference]

organelle membrane [inference]

nuclear membrane

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16632484 20152126 21565611 24356449 24469809 25088364 27979967
molecular adaptor activity	ISO
molecular adaptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pericentriolar material 1 protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
intraciliary transport involved in cilium assembly
microtubule anchoring at centrosome
protein localization to centrosome

Displaying **all 2** entries
InterPro
Pericentriolar material 1 protein, C-terminal
Pericentriolar material 1 protein

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5108	Xenbase:XB-GENE-958591	HUMAN92700
Xenopus tropicalis	18536	Xenbase:XB-GENE-958591
Rattus norvegicus	81740		RATNO11164
Danio rerio	321709		DANRE18191
Takifugu rubripes	445938		TAKRU16383
Pan troglodytes	464020		PANTR42044
Canis lupus familiaris	475618		CANLF04757
Bos taurus	525337		BOVIN21987
Macaca mulatta	703580		MACMU43642
Monodelphis domestica	100021226		MONDO26259

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Last updated: December 8, 2025