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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum lumen | ||
| neuron projection | ||
| nucleoplasm | ||
| dendrite |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Peptidase S8/S53 domain |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101098130 | FELCA07497 | |||
| 101144581 | GORGO22449 | |||
| 101327547 | TURTR14038 | |||
| 101566975 | 10160_0:0026bd | OCTDE14299 | ||
| 101596368 | 51337_0:00289d | JACJA20647 | ||
| 101710029 | 10181_0:000c5f | HETGA00677 | ||
| 101871682 | MELUD10892 | |||
| 101970522 | 43179_0:004388 | ICTTR08165 | ||
| 101993284 | 79684_0:003b33 | |||
| 102008940 | 34839_0:000fd3 | CHILA04959 |
