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proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum lumen | ||
| neuron projection | ||
| nucleoplasm | ||
| dendrite |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100534405 | ORENI14350 | |||
| 100606456 | NOMLE07461 | |||
| 100659343 | LOXAF12909 | |||
| 100727607 | 10141_0:003f29 | CAVPO04717 | ||
| 100771130 | 10029_0:003f3c | CRIGR17566 | ||
| 100925659 | SARHA13452 | |||
| 100995237 | PANPA21892 | |||
| 101018120 | PAPAN11305 | |||
| 101032326 | SAIBB21775 | |||
| 101068590 | TAKRU40062 |
